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Doctor's Best SAMe 400 Double Strength 60 Enteric Coated Tablets



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2 $70.19 Up to $3.60
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  • Description

    • Science-Based Nutrition

    • Dietary Supplement with 400 mg Active S-Adenosyl Methionine Per Tablet

    • Enhances Mood & Neural Function

    • Promotes Joint Comfort & Mobility

    • Supports Liver Health & Detoxification

    • Pharmaceutical Grade

    • Sealed in Blister Packs for Freshness & Convenience

    • Suitable for Vegetarians

      S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. Doctor's Best SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

      Supplementing with Double Strength SAMe 400

      The manufacturing process of Doctor's Best SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

      Double Strength SAMe 400 and Joint Function

      Doctors best double strength same 400 may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

      Double Strength SAMe 400 and Neural Health

      SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

      Double Strength SAMe 400 and Liver Function

      Double Strength SAMe 400 enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver production. Studies show Double Strength SAMe 400 may protect liver tissue from injury caused by a number of toxins.

      Our Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent Doctors best double strength SAMe 400 product with the highest percentage of the active S,S form per serving, bar none.

      Double Strength SAMe 400 is sealed in blister packs for freshness and stability.

      Suggested Use Of Double Strength SAMe 400

      Adult Use: Take 1 Double Strength SAMe 400 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.

      Other Ingredients of Double Strength SAMe 400

      Cellulose gel, methacrylic acid copolymer, compritol 888ATO, talc, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silica, medium chain triglycerides, sodium starch glycolate and iron oxide.

      The SAMe found in Double Strength SAMe 400 is free from yeast, dairy, gluten, soy, wheat and artificial flavoring.

      Contains nothing other than listed ingredients.


      Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with Doctor's Best SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

      Store product in a cool, dry place to ensure maximum quality.

    Supplement Facts of Double Strength SAMe 400

    Serving Size: 1 tablet

    Servings Per Container: 60 servings


    Amount per serving

    % Daily Value

    S-Adenosyl Methionine (from 800 mg SAMe tosylate disulfate)

    400 mg

    Daily Value not established.


  • Potency 400 mg
    Shipping Weight 0.12 kg
    Product SKU 477
    UPC Code 753950002524
    Brand Doctor's Best
    Dimensions 4.6 x 8.4 x 16 cm , 0.07 kg
    Package Quantity 30 Enteric Coated Tablets
    Substance Terms supplement
    Form of the product Tablets
    Google Product Category Health & Beauty, Health Care Fitness & Nutrition, Vitamins & Supplements
    Google Product Category ID 525
    Shipping Price $9.95
    Shipping Country Australia
    Conditions New

Doctor's Best SAMe 400 Double Strength 60 Enteric Coated Tablets Reviews


Very happy

I started using Megavitamins. Very happy with their best price and free shipping. I always get free shipping when I order over $130. No complaints. Will continue to order.


    Great Product

    I am very happy with the results; with Doctor's Best SAMe 400 Double Strength. This product works great on me. Last one year I am using this product. Today my health is better. It works on my joints and back pain.

      Write a review

      Doctor's Best SAMe 400 Double Strength 60 Enteric Coated Tablets

      Doctor's Best SAMe 400 Double Strength 60 Enteric Coated Tablets

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